Bifidobacterium longum subsp. longum Remodeled Roseburia and Phosphatidylserine Levels, Ameliorated Intestinal Disorders and liver Metabolic Abnormalities Induced by High-Fat Diet

Obesity is a growing global health concern, often leading to serious conditions such as hypertension, type 2 diabetes, and cardiovascular diseases. The imbalance between energy intake and metabolism is a primary cause of obesity. However, emerging research suggests that probiotics, like Bifidobacterium longum subsp. longum BL21 (BL21), can play a crucial role in regulating intestinal flora, thereby inhibiting obesity and improving metabolic disorders.

Wecare Probiotics Co., Ltd., a national high-tech enterprise, is at the forefront of this research. Specializing in the development and application of probiotic strains, the company offers a range of products including bifidobacterium probiotic powder, which is gaining attention for its health benefits.

Introduction

This study used the Bifidobacterium longum subsp. longum BL21 to intervene in high-fat feed induced obese mice, exploring the effect of BL21 on obese mice, providing efficacy support for BL21 in controlling weight, lowering blood lipids, and regulating intestinal microbiota.

Study Design

Main Results

BL21 attenuated weight gain

Total Cholesterol

Triglycerides

Low-density lipoprotein cholesterol

BL21 showed the lipid-lowering activity

BL21 ameliorated fat vacuolization in liver cells and epididymal fat accumulate ion, protected liver.

BL21 restored the gut microbiota diversity

Restored F/B

Increased Akkermansia

BL21 regulated the gut microbiota disorder

Conclusion：

• Continuous intervention with BL21 (1 B CFU/d for 8 weeks can effectively suppress obesity caused by a high-fat diet

• BL21 has lipid-lowering activity and balancing intestinal effect.

Wecare Probiotics Co., Ltd. is committed to leveraging the power of probiotics like Bifidobacterium Longum BL21 to enhance human health. With a focus on quality and innovation, the company continues to develop effective probiotic solutions for various fields, including food, health food, precision medicine, and more.

For those seeking natural ways to combat obesity and improve metabolic health, Bifidobacterium Longum BL21, backed by Wecare Probiotics' expertise, offers a promising solution.